POM TR. 033 318 421
(Distribution Permit Number from Board of Drug and Food Control the Republic of Indonesia)

Pharmacology

 is a Ganoderma lucidum polysaccharide peptide (GLPP) extract from mycelia cell membrane. Each  capsule contains 250 mg of polysaccharide peptide. In which it has 180 mg β-1,3/1,6-D-Glucan.

β-1,3/1,6-D-Glucan is an immunomodulator that modulates immune cell activities, especially macrophages. β-1,3/1,6-D-Glucan works on several human immune receptors such as Dectin-1 (the main receptor), Toll-like Receptor 2 and 6 (TLR-2 and -6), Scavenger Receptor, Complement Receptor 3 (CR3), and Lactosylceramide. It induces a group of immune cells such as macrophages, neutrophils, monocytes, Natural Killer (NK) cells and dendritic cells to modulate the innate and adaptive immune responses. β-1,3/1,6-D-Glucan is then absorbed by colon peyer patch, and later on phagocyted and degraded by macrophages. Macrophages that contain β-1,3/1,6-D-Glucan will circulate in the spleen and lymph nodes and release smaller fractions of β-1,3/1,6-D-Glucan particles to activate other immune cells. In bone marrow these macrophages will also release β-1,3/1,6-D-Glucan particles to activate bone marrow stem cells.(1,2)

* for detailed information, please see product application

Composition

  • Extract of Ganoderma lucidum polysaccharide peptide (GLPP) containing 180 mg β-1,3/1,6-D-Glucan ……………………………………………………………………………………………………………              250 mg
  • Filler …………………………………………………………………………………………………..               100 mg

Indication

To modulate the immune system (immunomodulator) and to be used as a complementary therapy against cancer, cardiovascular diseases, diabetic foot ulcer, and in vascular endothelial disturbances.

Contraindication

  • Pregnancy and lactation
  • Children below 5 years old
  • Hypersensitivity

Precaution

  • Stop using when undesirable symptoms occurred. Please consult your doctor

Adverse Reaction

  • Sub febrile and allergic reaction is rare, but can occur in few people (individually)

Dose

  • 1 capsule, 3 times daily

Administration

  • ½ hour before or 2 hours after meals

Storage

  • Keep in dry and cool place, avoid direct sun contact
  • Put in the refrigerator (4-100C) after the seal is opened
  • Keep away from children

Packaging

Box of bottle 30 capsules @250 mg Ganoderma lucidum polysaccharide Peptide extract containing 180 mg β-1,3/1,6-D-Glucan

 

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